Mitochondria transfer reverses the inhibitory effects of low stiffness on osteogenic differentiation of human mesenchymal stem cells

Mitochondria transfer reverses the inhibitory effects of low stiffness on osteogenic differentiation of human mesenchymal stem cells

Microenvironment biophysical factors such as matrix stiffness can noticeably affect the differentiation of mesenchymal stem cells (MSCs). In this mechanobiology transduction process, mitochondria are shown to be an active participant. The present study aims to systematically elucidate the phenotypic...

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Bibliographic Details
Main Authors: Shaoyang Ma, Rui Ding, Jiao Cao, Zhongbo Liu, Ang Li, Dandan Pei
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:European Journal of Cell Biology
Subjects:
Osteogenesis
PDLSCs
Matrix stiffness
Mitochondria
Mitochondria transfer
Online Access:http://www.sciencedirect.com/science/article/pii/S0171933523000122

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http://www.sciencedirect.com/science/article/pii/S0171933523000122

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