Mapping eQTL by leveraging multiple tissues and DNA methylation

Mapping eQTL by leveraging multiple tissues and DNA methylation

Abstract Background DNA methylation is an important tissue-specific epigenetic event that influences transcriptional regulation of gene expression. Differentially methylated CpG sites may act as mediators between genetic variation and gene expression, and this relationship can be exploited while map...

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Bibliographic Details
Main Authors: Chaitanya R. Acharya, Kouros Owzar, Andrew S. Allen
Format: Article
Language:English
Published: BMC 2017-10-01
Series:BMC Bioinformatics
Subjects:
eQTL
Multiple tissues
Tissue-specificity
DNA methylation
CpG islands
Gene expression
Online Access:http://link.springer.com/article/10.1186/s12859-017-1856-9

Internet

http://link.springer.com/article/10.1186/s12859-017-1856-9

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