Point-specific interactions of isovitexin with the neighboring amino acid residues of the hACE2 receptor as a targeted therapeutic agent in suppressing the SARS-CoV-2 influx mechanism

Point-specific interactions of isovitexin with the neighboring amino acid residues of the hACE2 receptor as a targeted therapeutic agent in suppressing the SARS-CoV-2 influx mechanism

Objective: Despite the development of several vaccines against severe acute respiratory syndrome coronavirus-2, the need for an additional prophylactic agent is evident. In recent in silico studies, isovitexin exhibited a higher binding affinity against the human angiotensin converting-enzyme 2 (hAC...

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Bibliographic Details
Main Authors: Nourin Ferdausi, Samarth Islam, Fahmida Hoque Rimti, Syeda Tasnim Quayum, Efat Muhammad Arshad, Aashian Ibnat, Tamnia Islam, Adittya Arefin, Tanzila Ismail Ema, Partha Biswas, Dipta Dey, Salauddin Al Azad
Format: Article
Language:English
Published: Network for the Veterinarians of Bangladesh 2022-06-01
Series:Journal of Advanced Veterinary and Animal Research
Subjects:
phytochemical; isovitexin; covid-19; molecular docking; dynamic simulation; hace2 receptor; prophylactic agent; target specificity
Online Access:http://www.ejmanager.com/fulltextpdf.php?mno=133112

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http://www.ejmanager.com/fulltextpdf.php?mno=133112

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