Benzyl isothiocyanate but not benzyl nitrile from Brassicales plants dually blocks the COX and LOX pathway in primary human immune cells

Benzyl isothiocyanate but not benzyl nitrile from Brassicales plants dually blocks the COX and LOX pathway in primary human immune cells

The main products formed from glucosinolates from Brassicales plants are isothiocyanates (ITCs) and nitriles. ITCs are known for their diverse bioactive potential, knowledge about the bioactivity of food-borne nitriles is poor, though. Anti-inflammation by benzyl ITC (BITC) and its nitrile has not s...

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Bibliographic Details
Main Authors: Corinna Herz, Melinda-Rita Márton, Hoai Thi Thu Tran, Carsten Gründemann, Jana Schell, Evelyn Lamy
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Journal of Functional Foods
Subjects:
Benzyl isothiocyanate
BITC
Brassicales
Anti-inflammatory effect in primary human PBMC
Benzyl nitrile
Dual LOX and COX pathway inhibitor
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464616000906

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http://www.sciencedirect.com/science/article/pii/S1756464616000906

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