Targeted DNA Methylation Editing Using an All-in-One System Establishes Paradoxical Activation of <i>EBF3</i>

Targeted DNA Methylation Editing Using an All-in-One System Establishes Paradoxical Activation of <i>EBF3</i>

Cutaneous melanoma is rapidly on the rise globally, surpassing the growth rate of other cancers, with metastasis being the primary cause of death in melanoma patients. Consequently, understanding the mechanisms behind this metastatic process and exploring innovative treatments is of paramount import...

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Bibliographic Details
Main Authors: Rakesh Banerjee, Priyadarshana Ajithkumar, Nicholas Keestra, Jim Smith, Gregory Gimenez, Euan J. Rodger, Michael R. Eccles, Jisha Antony, Robert J. Weeks, Aniruddha Chatterjee
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cancers
Subjects:
epigenomic editing
All-in-one CRISPR system
DNA methylation
paradoxical role
melanoma
RNA-sequencing
Online Access:https://www.mdpi.com/2072-6694/16/5/898

Internet

https://www.mdpi.com/2072-6694/16/5/898

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