Discordance between chromatin accessibility and transcriptional activity during the human primed-to-naïve pluripotency transition process

Abstract Naïve pluripotent state can be obtained by several strategies from various types of cells, in which the cell fate roadmap as well as key biological events involved in the journey have been described in detail. Here, we carefully explored the chromatin accessibility dynamics during the prime...

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Bibliographic Details
Main Authors: Zhifen Tu, Yan Bi, Tengyan Mao, Hong Wang, Shaorong Gao, Yixuan Wang
Format: Article
Language:English
Published: SpringerOpen 2023-11-01
Series:Cell Regeneration
Subjects:
Online Access:https://doi.org/10.1186/s13619-023-00179-2