Incorporation of real-time PCR into routine public health surveillance of culture negative bacterial meningitis in São Paulo, Brazil.

Real-time (RT)-PCR increases diagnostic yield for bacterial meningitis and is ideal for incorporation into routine surveillance in a developing country. We validated a multiplex RT-PCR assay for Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae in Brazil. Risk factors for...

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Bibliographic Details
Main Authors: Claudio T Sacchi, Lucila O Fukasawa, Maria G Gonçalves, Maristela M Salgado, Kathleen A Shutt, Telma R Carvalhanas, Ana F Ribeiro, Brigina Kemp, Maria C O Gorla, Ricardo K Albernaz, Eneida G L Marques, Angela Cruciano, Eliseu A Waldman, M Cristina C Brandileone, Lee H Harrison, São Paulo RT-PCR Surveillance Project Team
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3120771?pdf=render