The Landscape of Actionable Genomic Alterations by Next-Generation Sequencing in Tumor Tissue Versus Circulating Tumor DNA in Chinese Patients With Non-Small Cell Lung Cancer

The Landscape of Actionable Genomic Alterations by Next-Generation Sequencing in Tumor Tissue Versus Circulating Tumor DNA in Chinese Patients With Non-Small Cell Lung Cancer

BackgroundCirculating tumor DNA (ctDNA) sequence analysis shows great potential in the management of non-small cell lung cancer (NSCLC) and the prediction of drug sensitivity or resistance in many cancers. Here, we drew and compared the somatic mutational profile using ctDNA and tumor tissue sequenc...

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Bibliographic Details
Main Authors: Jun Cai, Huihui Jiang, Shuqing Li, Xiaoxia Yan, Meng Wang, Na Li, Cuimin Zhu, Hui Dong, Dongjuan Wang, Yue Xu, Hui Xie, Shouxin Wu, Jingwei Lou, Jiangman Zhao, Qingshan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Oncology
Subjects:
NSCLC
tissue
ctDNA
genomic subtyping
targeted therapy response
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.751106/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.751106/full

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