Association of Marek's Disease induced immunosuppression with activation of a novel regulatory T cells in chickens.

Marek's Disease Virus (MDV) is an alphaherpesvirus that infects chickens, transforms CD4+ T cells and causes deadly lymphomas. In addition, MDV induces immunosuppression early during infection by inducing cell death of the infected lymphocytes, and potentially due to activation of regulatory T...

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Detalhes bibliográficos
Main Authors: Angila Gurung, Nitin Kamble, Benedikt B Kaufer, Ansar Pathan, Shahriar Behboudi
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science (PLoS) 2017-12-01
Colecção:PLoS Pathogens
Acesso em linha:https://doi.org/10.1371/journal.ppat.1006745