Different inflammatory, fibrotic, and immunologic signatures between pre-fibrotic and overt primary myelofibrosis

Primary myelofibrosis (PMF) is a myeloid proliferative neoplasm (MPN) characterized by bone marrow (BM) fibrosis. Pre-fibrotic PMF (pre-PMF) progresses to overt PMF. Megakaryocytes (MKs) play a primary role in PMF; however, the functions of MK subsets and those of other hematopoietic cells during P...

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Bibliographic Details
Main Authors: Seung-Hyun Jung, Sung-Eun Lee, Sujin Yun, Da-Eun Min, Youngjin Shin, Yeun-Jun Chung, Sug Hyung Lee
Format: Article
Language:English
Published: Ferrata Storti Foundation 2024-10-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/11780