A Mechanism of Double-Membrane Vesicle Formation from Liquid-Ordered/Liquid-Disordered Phase Separated Spherical Membrane

Genome replication of coronaviruses takes place in specific cellular compartments, in so-called double-membrane vesicles (DMVs), formed from the endoplasmic reticulum (ER). An intensive production of DMVs is induced by non-structural viral proteins. Here, we proposed a possible mechanism of the DMV...

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Bibliographic Details
Main Authors: Oleg V. Kondrashov, Sergey A. Akimov
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Membranes
Subjects:
Online Access:https://www.mdpi.com/2077-0375/13/1/25