Development and Characterization of Glimepiride Novel Solid Nanodispersion for Improving Its Oral Bioavailability

Glimepiride is an antidiabetic drug which is one of the third generation sulfonylureas. It belongs to class II, according to the BCS (Biopharmaceutical Classification System), which is characterized by low solubility and high permeability. The aim of this work was to formulate glimepiride as solid d...

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Bibliographic Details
Main Authors: Mona Qushawy, Ali Nasr, Shady Swidan, Yasmin Mortagi
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Scientia Pharmaceutica
Subjects:
Online Access:https://www.mdpi.com/2218-0532/88/4/52