Rhabdastrellic acid-A induced autophagy-associated cell death through blocking Akt pathway in human cancer cells.

Rhabdastrellic acid-A induced autophagy-associated cell death through blocking Akt pathway in human cancer cells.

BACKGROUND: Autophagy is an evolutionarily conserved protein degradation pathway. A defect in autophagy may contribute to tumorigenesis. Autophagy inducers could have a potential function in tumor prevention and treatment. METHODOLOGY/PRINCIPAL FINDINGS: Our results showed that Rhabdastrellic acid-A...

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Main Authors: Dan-Dan Li, Jing-Feng Guo, Jia-Jia Huang, Lin-Lin Wang, Rong Deng, Jian-Nan Liu, Gong-Kan Feng, Ding-Jun Xiao, Song-Zhi Deng, Xiao-Shi Zhang, Xiao-Feng Zhu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2923153?pdf=render

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http://europepmc.org/articles/PMC2923153?pdf=render

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