A time out for CENP-A

A time out for CENP-A

Proper chromosome segregation relies on a functional centromere–kinetochore interface. We showed that chromatin containing CENtromere Protein A (CENP-A) is essential for centromere assembly, but dispensable for chromosome segregation in the presence of CENP-B-bound DNA sequences. This demonstrates t...

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Bibliographic Details
Main Authors: S. Hoffmann, D. Fachinetti
Format: Article
Language:English
Published: Taylor & Francis Group 2017-05-01
Series:Molecular & Cellular Oncology
Subjects:
auxin
cancer
cenp-a
cenp-b
cenp-c
centromere
chromosome segregation
histone depletion
mitosis
protein degradation
Online Access:http://dx.doi.org/10.1080/23723556.2017.1293596

Internet

http://dx.doi.org/10.1080/23723556.2017.1293596

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