Lung Extracellular Matrix Hydrogels Enhance Preservation of Type II Phenotype in Primary Alveolar Epithelial Cells

Lung Extracellular Matrix Hydrogels Enhance Preservation of Type II Phenotype in Primary Alveolar Epithelial Cells

One of the main limitations of in vitro studies on lung diseases is the difficulty of maintaining the type II phenotype of alveolar epithelial cells in culture. This fact has previously been related to the translocation of the mechanosensing Yes-associated protein (YAP) to the nuclei and Rho signali...

Full description

Bibliographic Details
Main Authors: Esther Marhuenda, Alvaro Villarino, Maria Leonor Narciso, Marta Camprubí-Rimblas, Ramon Farré, Núria Gavara, Antonio Artigas, Isaac Almendros, Jorge Otero
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
extracellular matrix
hydrogels
alveolar cells
type II phenotype
YAP
Online Access:https://www.mdpi.com/1422-0067/23/9/4888

Internet

https://www.mdpi.com/1422-0067/23/9/4888

Similar Items