Endothelial dysfunction due to the inhibition of the synthesis of nitric oxide: Proposal and characterization of an in vitro cellular model

Endothelial dysfunction due to the inhibition of the synthesis of nitric oxide: Proposal and characterization of an in vitro cellular model

The vascular endothelium plays a pivotal role in the maintenance of vascular homeostasis, mediated by vasoactive molecules produced by endothelial cells. The balance between vasoconstrictor and vasodilator biomolecules is what guarantees this equilibrium. Therefore, an increase in the bioavailabilit...

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Bibliographic Details
Main Authors: Fernanda Cardoso da Silva, Bruna Juber de Araújo, Carina Santos Cordeiro, Vinícius Marques Arruda, Bruno Quintanilha Faria, Joyce Ferreira Da Costa Guerra, Thaise Gonçalves De Araújo, Cristina Ribas Fürstenau
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Physiology
Subjects:
endothelial dysfunction
nitric oxide
p22phox
NOX4
IL-6
ACE
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.978378/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2022.978378/full

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