Identification of regions in multiple sequence alignments thermodynamically suitable for targeting by consensus oligonucleotides: application to HIV genome

Identification of regions in multiple sequence alignments thermodynamically suitable for targeting by consensus oligonucleotides: application to HIV genome

<p>Abstract</p> <p>Background</p> <p>Computer programs for the generation of multiple sequence alignments such as "Clustal W" allow detection of regions that are most conserved among many sequence variants. However, even for regions that are equally conserved,...

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Bibliographic Details
Main Authors: Matveeva Olga V, Foley Brian T, Nemtsov Vladimir A, Gesteland Raymond F, Matsufuji Senya, Atkins John F, Ogurtsov Aleksey Y, Shabalina Svetlana A
Format: Article
Language:English
Published: BMC 2004-04-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/5/44

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http://www.biomedcentral.com/1471-2105/5/44

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