Sex, Race, and Age Differences of Cardiovascular Outcomes in Cardiac Resynchronization Therapy RCTs: A Systematic Review and Meta-analysis

Background: Cardiac resynchronization therapy (CRT) is beneficial in patients who have heart failure with reduced ejection fraction or arrhythmic events. However, most randomized controlled trials (RCTs) showing survival benefits primarily enrolled older white men. This study aims to evaluate CRT ef...

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Main Authors: Bradley McKay, BHSc, Nicholas W.H. Tseng, BSc-c, Hassan I. Sheikh, BHSc-c, Mohammad K. Syed, BHSc, Maureen Pakosh, BA MISt, Jessica E. Caterini, MD, PhD, Abhinav Sharma, MD, PhD, Tracey J.F. Colella, RN, PhD, Kaja M. Konieczny, MD, Kim A. Connelly, MBBS PhD, Michelle M. Graham, MD, Michael McDonald, MD, Laura Banks, PhD, Varinder Kaur Randhawa, MD, PhD
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:CJC Open
Online Access:http://www.sciencedirect.com/science/article/pii/S2589790X21002390