Identification of Molecules from Coffee Silverskin That Suppresses Myostatin Activity and Improves Muscle Mass and Strength in Mice

Identification of Molecules from Coffee Silverskin That Suppresses Myostatin Activity and Improves Muscle Mass and Strength in Mice

Coffee has been shown to attenuate sarcopenia, the age-associated muscle atrophy. Myostatin (MSTN), a member of the TGF-β growth/differentiation factor superfamily, is a potent negative regulator of skeletal muscle mass, and MSTN-inhibition increases muscle mass or prevents muscle atrophy. This stud...

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Bibliographic Details
Main Authors: Jeong Han Kim, Jae Hong Kim, Jun-Pil Jang, Jae-Hyuk Jang, Deuk-Hee Jin, Yong Soo Kim, Hyung-Joo Jin
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
coffee silverskin
myostatin inhibition
muscle atrophy
<i><sup>β</sup>N</i>-arachinoyl−5-hydroxytryptamide
<i><sup>β</sup>N</i>-behenoyl−5-hydroxytryptamid
Online Access:https://www.mdpi.com/1420-3049/26/9/2676

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https://www.mdpi.com/1420-3049/26/9/2676

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