Higher polymerase activity of a human influenza virus enhances activation of the hemagglutinin-induced Raf/MEK/ERK signal cascade

<p>Abstract</p> <p>Influenza viruses replicate within the nucleus of infected cells. Viral genomic RNA, three polymerase subunits (PB2, PB1, and PA), and the nucleoprotein (NP) form ribonucleoprotein complexes (RNPs) that are exported from the nucleus late during the infectious cyc...

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Bibliographic Details
Main Authors: Webster Robert G, Franks John, Yen Hui-Ling, Marjuki Henju, Pleschka Stephan, Hoffmann Erich
Format: Article
Language:English
Published: BMC 2007-12-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/4/1/134