Mapping mammalian cell-type-specific transcriptional regulatory networks using KD-CAGE and ChIP-seq data in the TC-YIK cell line.

Mapping mammalian cell-type-specific transcriptional regulatory networks using KD-CAGE and ChIP-seq data in the TC-YIK cell line.

Mammals are composed of hundreds of different cell types with specialized functions. Each of these cellular phenotypes are controlled by different combinations of transcription factors. Using a human non islet cell insulinoma cell line (TC-YIK) which expresses insulin and the majority of known pancr...

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Bibliographic Details
Main Authors: Marina eLizio, Yuri eIshizu, Masayoshi eItoh, Timo eLassmann, Akira eHasegawa, Atsutaka eKubosaki, Jessica eSeverin, Hideya eKawaji, Yukio eNakamura, Harukazu eSuzuki, Yoshihide eHayashizaki, Piero eCarninci, Alistair R R Forrest
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Genetics
Subjects:
Insulin
Systems Biology
Transcription Factors
Network analysis
ChIP-seq
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00331/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00331/full

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