PDGF, NGF, and EGF as main contributors to tumorigenesis in high-risk retinoblastoma

PDGF, NGF, and EGF as main contributors to tumorigenesis in high-risk retinoblastoma

Retinoblastoma (RB) is the most common form of eye cancer experienced in childhood. Its aggressive malignancy is associated with excellent survival rates in high-income countries; however, the prognosis in third-world countries is less favorable. Early diagnosis can maximize the patient’s visual out...

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Bibliographic Details
Main Authors: Karim Al-Ghazzawi, Michael Wessolly, Sami Dalbah, Petra Ketteler, Tobias Kiefer, Nikolaos Bechrakis, Jabbarli Leyla, Saskia Ting, Eva Biewald, Fabian D. Mairinger
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Oncology
Subjects:
retinoblastoma - epigenetics
retinoblastoma
PDGF = platelet-derived growth factor
MAPK/ERK2 pathway 1
pediatric cancer and oncology
biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1144951/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1144951/full

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