Identifying tumorigenic non-coding mutations through altered cis-regulation

Summary: Identification of non-coding mutations driving tumorigenesis requires alternative approaches to coding mutations. Enriched associations between mutated regulatory elements and altered cis-regulation in tumors are a promising approach to stratify candidate non-coding driver mutations. Here w...

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Bibliographic Details
Main Authors: Zhongshan Cheng, Michael Vermeulen, Micheal Rollins-Green, Tomas Babak, Brian DeVeale
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166721006407