Transcriptional landscape of Kaposi sarcoma tumors identifies unique immunologic signatures and key determinants of angiogenesis

Transcriptional landscape of Kaposi sarcoma tumors identifies unique immunologic signatures and key determinants of angiogenesis

Abstract Background Kaposi sarcoma (KS) is a multicentric tumor caused by Kaposi sarcoma herpesvirus (KSHV) that leads to morbidity and mortality among people with HIV worldwide. KS commonly involves the skin but can occur in the gastrointestinal tract (GI) in severe cases. Methods RNA sequencing wa...

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Bibliographic Details
Main Authors: Ramya Ramaswami, Takanobu Tagawa, Guruswamy Mahesh, Anna Serquina, Vishal Koparde, Kathryn Lurain, Sarah Dremel, Xiaofan Li, Ameera Mungale, Alex Beran, Zoe Weaver Ohler, Laura Bassel, Andrew Warner, Ralph Mangusan, Anaida Widell, Irene Ekwede, Laurie T. Krug, Thomas S. Uldrick, Robert Yarchoan, Joseph M. Ziegelbauer
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Translational Medicine
Online Access:https://doi.org/10.1186/s12967-023-04517-5

Internet

https://doi.org/10.1186/s12967-023-04517-5

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