Mitochondrial-Targeted Therapy for Doxorubicin-Induced Cardiotoxicity

Mitochondrial-Targeted Therapy for Doxorubicin-Induced Cardiotoxicity

Anthracyclines, such as doxorubicin, are effective chemotherapeutic agents for the treatment of cancer, but their clinical use is associated with severe and potentially life-threatening cardiotoxicity. Despite decades of research, treatment options remain limited. The mitochondria is commonly consid...

Full description

Bibliographic Details
Main Authors: Bin Bin Wu, Kam Tong Leung, Ellen Ngar-Yun Poon
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
doxorubicin (DOX)
cardiotoxicity
mitochondria
human pluripotent stem cells (hPSC)
anthracyclines
hPSC-cardiomyocytes
Online Access:https://www.mdpi.com/1422-0067/23/3/1912

Internet

https://www.mdpi.com/1422-0067/23/3/1912

Similar Items