Cancer stem cells promote lymph nodes metastasis of breast cancer by reprogramming tumor microenvironment

Cancer stem cells promote lymph nodes metastasis of breast cancer by reprogramming tumor microenvironment

Breast cancer progression and metastasis are governed by a complex interplay within the tumor immune microenvironment (TIME), involving numerous cell types. Lymph node metastasis (LNM) is a key prognostic marker associated with distant organ metastasis and reduced patient survival, but the mechanism...

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Bibliographic Details
Main Authors: Lin Li, Jianyu Liu, Wenzheng Wang, Yingqiang Fu, Yuhan Deng, Xin Li, Zhuolin Liu, Yuheng Pang, Yangyang Xu, Meisi Yan, Zhigao Li
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Translational Oncology
Subjects:
Breast cancer 1
Cancer stem cells (CSCs) 2
Tumor immune microenvironment (TIME) 3
Single-cell RNA sequencing (scRNA-seq) 4
Lymph node metastasis 5
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523323001195

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http://www.sciencedirect.com/science/article/pii/S1936523323001195

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