Thrombin generation capacity is enhanced by low antithrombin activity and depends on the activity of the related coagulation factors

Abstract Background Supplementation with antithrombin (AT) concentrates is now common in the treatment of congenital and acquired AT deficiency. However, there is no established consensus on the target and timing of supplementation. We aimed to elucidate the effects of AT deficiency on the balance b...

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Bibliographic Details
Main Authors: Takumi Tsuchida, Mineji Hayakawa, Shota Kawahara, Osamu Kumano
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Thrombosis Journal
Subjects:
Online Access:https://doi.org/10.1186/s12959-022-00388-w