$Collagen Specific T-Cell Repertoire and HLA-DR Alleles: Biomarkers of Active Refractory Rheumatoid Arthritis$

Collagen Specific T-Cell Repertoire and HLA-DR Alleles: Biomarkers of Active Refractory Rheumatoid Arthritis

Rheumatoid arthritis (RA) is characterized by chronic joint inflammation and associates with HLA-DRB1*04. The Collagen IIp261-273-specific T cell repertoire in the peripheral blood of DR4+ patients at the onset of the disease shows a restricted TCR-beta chain usage among which the most frequent is T...

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Bibliografische gegevens
Hoofdauteurs:	Gabriele Di Sante, Barbara Tolusso, Anna Laura Fedele, Elisa Gremese, Stefano Alivernini, Chiara Nicolò, Francesco Ria, Gianfranco Ferraccioli
Formaat:	Artikel
Taal:	English
Gepubliceerd in:	Elsevier 2015-12-01
Reeks:	EBioMedicine
Onderwerpen:	HLA-DRB1 Disease activity ACPA TRBV 25 Clonotypes
Online toegang:	http://www.sciencedirect.com/science/article/pii/S2352396415302036

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http://www.sciencedirect.com/science/article/pii/S2352396415302036

Collagen Specific T-Cell Repertoire and HLA-DR Alleles: Biomarkers of Active Refractory Rheumatoid Arthritis

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