Changes in dendritic complexity and spine morphology following BCG immunization in APP/PS1 mice

Changes in dendritic complexity and spine morphology following BCG immunization in APP/PS1 mice

Bacillus Calmette – Guerin (BCG) is an immune regulator that can enhance hippocampal synaptic plasticity in rats; however, it is unclear whether it can improve synaptic function in a mouse model with Alzheimer’s disease (AD). We hypothesized that BCG plays a protective role in AD mice and investigat...

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Bibliographic Details
Main Authors: Qingqing Li, Xiao Wang, Zhao Hua Wang, Zhenzong Lin, Jieyi Yang, Jichun Chen, Rui Wang, Wenfeng Ye, Ya Li, Yingying Wu, Aiguo Xuan
Format: Article
Language:English
Published: Taylor & Francis Group 2022-11-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
bcg
alzheimer’s disease
dendritic complexity
spine morphology
jak2/stat3
Online Access:http://dx.doi.org/10.1080/21645515.2022.2121568

Internet

http://dx.doi.org/10.1080/21645515.2022.2121568

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