α<sub>1</sub>-Acid Glycoprotein-Decorated Hyaluronic Acid Nanoparticles for Suppressing Metastasis and Overcoming Drug Resistance Breast Cancer

α<sub>1</sub>-Acid Glycoprotein-Decorated Hyaluronic Acid Nanoparticles for Suppressing Metastasis and Overcoming Drug Resistance Breast Cancer

Robust inflammation-suppressing nanoparticles based on α<sub>1</sub>-acid glycoprotein (AGP)-conjugated hyaluronic acid nanoparticles (AGP-HA NPs) were designed to regulate breast cancer cells’ sensitivity to chemotherapy and to suppress tumor metastasis. The successful conjugation betwe...

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Bibliographic Details
Main Authors: Haneen Omar, Roa’ Fardous, Yasser M. Alhindi, Alhassan H. Aodah, Mram Alyami, Mohammed S. Alsuabeyl, Waleed M. Alghamdi, Ali H. Alhasan, Abdulaziz Almalik
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biomedicines
Subjects:
multidrug resistance (MDR)
tumor metastasis
hyaluronic acid (HA) nanoparticles
α<sub>1</sub>-acid glycoprotein (AGP)
breast cancer cells
immune-suppressing nanoparticles
Online Access:https://www.mdpi.com/2227-9059/10/2/414

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https://www.mdpi.com/2227-9059/10/2/414

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