Effects of the CB1 Receptor Antagonists AM6545 and AM4113 on Insulin Resistance in a High-Fructose High-Salt Rat Model of Metabolic Syndrome

Effects of the CB1 Receptor Antagonists AM6545 and AM4113 on Insulin Resistance in a High-Fructose High-Salt Rat Model of Metabolic Syndrome

<i>Background and Objectives:</i> Insulin resistance (IR) is a serious condition leading to development of diabetes and cardiovascular complications. Hyper-activation of cannabinoid receptors-1 (CB1) has been linked to the development of metabolic disorders such as IR. Therefore, the eff...

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Bibliographic Details
Main Authors: Basma G. Eid, Thikryat Neamatallah, Abeer Hanafy, Hany M. El-Bassossy, Hibah M. Aldawsari, Kiran Vemuri, Alexandros Makriyannis
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Medicina
Subjects:
metabolic syndrome
cannabinoids
AM6545
AM4113
insulin resistance
Online Access:https://www.mdpi.com/1010-660X/56/11/573

Internet

https://www.mdpi.com/1010-660X/56/11/573

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