Microfluidics-based PLGA nanoparticles of ratiometric multidrug: From encapsulation and release rates to cytotoxicity in human lens epithelial cells

Multidrug nanomedicine is an effective therapeutic approach for the treatment of chronic diseases and cancers. However, co-encapsulation and release of drug combination at a fixed ratio by nanoparticles, particularly for long acting ocular formulations, remains challenging. Herein, poly (lactic-co-g...

Full description

Bibliographic Details
Main Authors: Yexuan Guo, Xinyang Li, Robert B. Macgregor, Jr., Hong Yan, Rui Xue Zhang
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023055263