Opposing Roles for the Related ETS-Family Transcription Factors Spi-B and Spi-C in Regulating B Cell Differentiation and Function

Opposing Roles for the Related ETS-Family Transcription Factors Spi-B and Spi-C in Regulating B Cell Differentiation and Function

Generation of specific antibodies during an immune response to infection or vaccination depends on the ability to rapidly and accurately select clones of antibody-secreting B lymphocytes for expansion. Antigen-specific B cell clones undergo the cell fate decision to differentiate into antibody-secre...

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Bibliographic Details
Main Authors: Anne-Sophie Laramée, Hannah Raczkowski, Peng Shao, Carolina Batista, Devanshi Shukla, Li Xu, S. M. Mansour Haeryfar, Yodit Tesfagiorgis, Steven Kerfoot, Rodney DeKoter
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
Spi-B
Spi-C
plasma cell
antibody
Bach2
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00841/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00841/full

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