IFNAR1 Deficiency Impairs Immunostimulatory Properties of Neutrophils in Tumor-Draining Lymph Nodes

IFNAR1 Deficiency Impairs Immunostimulatory Properties of Neutrophils in Tumor-Draining Lymph Nodes

Tumor-draining lymph nodes (TDLNs) are the first organs where the metastatic spread of different types of cancer, including head and neck cancer (HNC), occurs and have therefore high prognostic relevance. Moreover, first anti-cancer immune responses have been shown to be initiated in such LNs via tu...

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Bibliographic Details
Main Authors: Timon Hussain, Maksim Domnich, Sharareh Bordbari, Ekaterina Pylaeva, Elena Siakaeva, Ilona Spyra, Irem Ozel, Freya Droege, Anthony Squire, Stefan Lienenklaus, Kathrin Sutter, Anja Hasenberg, Matthias Gunzer, Stephan Lang, Jadwiga Jablonska
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
IFNAR1
Interferons
neutrophils
tumor-draining lymph nodes
neutrophils/T-cells interactions
intravital microscopy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.878959/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.878959/full

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