Generalisation of genomic findings and applications of polygenic risk scores

Abstract Polygenic Risk Scores (PRS) (also known as polygenic scores, genetic risk scores or polygenic indexes) capture genetic contributions of a multitude of markers that characterise complex traits. Although their likely application to precision medicine remains to be established, promising advan...

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Bibliographic Details
Main Authors: Manuel Corpas, Segun Fatumo
Format: Article
Language:English
Published: BMC 2023-07-01
Series:BMC Medical Genomics
Online Access:https://doi.org/10.1186/s12920-023-01615-7