Aldh1a1 and additional markers of dopamine cell heterogeneity in substantia nigra and ventral tegmental area identified as preserved in two transgenic α-synuclein mouse models of neurodegenerative disease

Aim: Parkinson’s disease (PD) is characterized by degeneration of midbrain dopamine neurons and synucleinopathy [aggregated alpha-synuclein protein (αSyn)]. The correlation between αSyn pathology and dopamine neuron degeneration remains to be fully established. Mouse models of PD are commonly used t...

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Bibliographic Details
Main Authors: Bianca Vlcek, Sylvie Dumas, Sara Ekmark-Lewén, Eleonora Rubino, Martin Ingelsson, Åsa Wallén-Mackenzie
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2023-10-01
Series:Exploration of Neuroprotective Therapy
Subjects:
Online Access:https://www.explorationpub.com/Journals/ent/Article/100453