Evaluation and comparison of pharmacokinetic profiles and safety of two extended-release buprenorphine formulations in common marmosets (Callithrix jacchus)

Abstract While sustained-release buprenorphine (BSR) is used as a long-lasting opioid analgesic in common marmosets (Callithrix jacchus), there are no published studies on pharmaceutical-grade extended-release buprenorphine options such as Ethiqa XR (EXR) for this species. However, BSR is a compound...

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Bibliographic Details
Main Authors: Niora J. Fabian, Anthony J. Mannion, Morgan Jamiel, David. J. Anderson, Joseph E. Rower, Christopher A. Reilly, William Menegas, Sureshkumar Muthupalani, Christina Ta, James G. Fox, Robin Kramer, Jennifer L. Haupt
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-38973-2