Increased renal function decline in fast metabolizers using extended-release tacrolimus after kidney transplantation

Increased renal function decline in fast metabolizers using extended-release tacrolimus after kidney transplantation

Abstract Fast metabolism of immediate-release tacrolimus (IR-Tac) is associated with decreased kidney function after renal transplantation (RTx) compared to slow metabolizers. We hypothesized, by analogy, that fast metabolism of extended-release tacrolimus (ER-Tac) is associated with worse renal fun...

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Bibliographic Details
Main Authors: Gerold Thölking, Brigitte Filensky, Ulrich Jehn, Katharina Schütte-Nütgen, Raphael Koch, Christine Kurschat, Hermann Pavenstädt, Barbara Suwelack, Stefan Reuter, Dirk Kuypers
Format: Article
Language:English
Published: Nature Portfolio 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95201-5

Internet

https://doi.org/10.1038/s41598-021-95201-5

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