Sex-specific differences in cardiac function, inflammation and injury during early polymicrobial sepsis

Take-home message Sex differences in sepsis are underexplored, even though female sex appears to be cardioprotective in early sepsis. In early normovolaemic polymicrobial sepsis, hyperdynamic response occurs in males, whereas myocardial stress/injury is limited in females, in part mediated by less c...

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Bibliographic Details
Main Authors: Sophie L. M. Walker, Chand Muthoo, Jenifer Sanchez, Ana Gutierrez Del Arroyo, Gareth L. Ackland
Format: Article
Language:English
Published: SpringerOpen 2022-06-01
Series:Intensive Care Medicine Experimental
Subjects:
Online Access:https://doi.org/10.1186/s40635-022-00454-7