Platelet-rich plasma inhibits inflammation, apoptosis, and the NLRP3/Caspase-1 pathway and induces matrix metalloproteinases and proliferation of IL-1β-induced articular chondrocytes by downregulating T-box transcription factor 3

Objectives Osteoarthritis (OA) is a chronic joint disease characterized by osteoproliferation and the degeneration and destruction of articular cartilage. Platelet-rich plasma (PRP) is rich in various growth factors that have been reported to promote bone defect repair. This study examined the speci...

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Bibliographic Details
Main Authors: Feng Zhuo, Jun Li, Yong-Hong Wang, Ming Li, Fang-Fei Song, Yu-Liang Liu, Zong-Yu Tao
Format: Article
Language:English
Published: SAGE Publishing 2022-05-01
Series:European Journal of Inflammation
Online Access:https://doi.org/10.1177/1721727X221093056