The spike glycoprotein of highly pathogenic human coronaviruses: structural insights for understanding infection, evolution and inhibition

The spike glycoprotein of highly pathogenic human coronaviruses: structural insights for understanding infection, evolution and inhibition

Highly pathogenic human coronaviruses (CoV) including SARS‐CoV, MERS‐CoV and SARS‐CoV‐2 have emerged over the past two decades, resulting in infectious disease outbreaks that have greatly affected public health. The CoV surface spike (S) glycoprotein mediates receptor binding and membrane fusion for...

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Bibliographic Details
Main Authors: Shuyuan Qiao, Shuyuan Zhang, Jiwan Ge, Xinquan Wang
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:FEBS Open Bio
Subjects:
evolution
highly pathogenic coronaviruses
infection
inhibition
spike glycoprotein
structural insights
Online Access:https://doi.org/10.1002/2211-5463.13454

Internet

https://doi.org/10.1002/2211-5463.13454

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