Factor H-Dependent Alternative Pathway Inhibition Mediated by Porin B Contributes to Virulence of <named-content content-type="genus-species">Neisseria meningitidis</named-content>
ABSTRACT The identification of “factor H binding protein (fHbp)-null” invasive meningococcal isolates and the realization that widespread use of fHbp-based vaccines could herald selection of such strains prompted us to characterize novel mechanisms of alternative pathway (AP) inhibition on meningoco...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2013-11-01
|
| Series: | mBio |
| Online Access: | https://journals.asm.org/doi/10.1128/mBio.00339-13 |