Factor H-Dependent Alternative Pathway Inhibition Mediated by Porin B Contributes to Virulence of <named-content content-type="genus-species">Neisseria meningitidis</named-content>

Factor H-Dependent Alternative Pathway Inhibition Mediated by Porin B Contributes to Virulence of <named-content content-type="genus-species">Neisseria meningitidis</named-content>

ABSTRACT The identification of “factor H binding protein (fHbp)-null” invasive meningococcal isolates and the realization that widespread use of fHbp-based vaccines could herald selection of such strains prompted us to characterize novel mechanisms of alternative pathway (AP) inhibition on meningoco...

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Bibliographic Details
Main Authors: Lisa A. Lewis, David M. Vu, Shreekant Vasudhev, Jutamas Shaughnessy, Dan M. Granoff, Sanjay Ram
Format: Article
Language:English
Published: American Society for Microbiology 2013-11-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00339-13

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