Targeting the Cdc2‐like kinase 2 for overcoming platinum resistance in ovarian cancer

Targeting the Cdc2‐like kinase 2 for overcoming platinum resistance in ovarian cancer

Abstract Platinum resistance represents a major barrier to the survival of patients with ovarian cancer (OC). Cdc2‐like kinase 2 (CLK2) is a major protein kinase associated with oncogenic phenotype and development in some solid tumors. However, the exact role and underlying mechanism of CLK2 in the...

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Bibliographic Details
Main Authors: Yinan Jiang, Shuting Huang, Lan Zhang, Yun Zhou, Wei Zhang, Ting Wan, Haifeng Gu, Yi Ouyang, Xiaojing Zheng, Pingping Liu, Baoyue Pan, Huiling Xiang, Mingxiu Ju, Rongzhen Luo, Weihua Jia, Shenjiao Huang, Jundong Li, Min Zheng
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:MedComm
Subjects:
Cdc2‐like kinase 2
DNA damage repair
ovarian cancer
platinum resistance
synergistic lethal
Online Access:https://doi.org/10.1002/mco2.537

Internet

https://doi.org/10.1002/mco2.537

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