8-OxoG-Dependent Regulation of Global Protein Responses Leads to Mutagenesis and Stress Survival in <i>Bacillus subtilis</i>

8-OxoG-Dependent Regulation of Global Protein Responses Leads to Mutagenesis and Stress Survival in <i>Bacillus subtilis</i>

The guanine oxidized (GO) system of <i>Bacillus subtilis</i>, composed of the YtkD (MutT), MutM and MutY proteins, counteracts the cytotoxic and genotoxic effects of the oxidized nucleobase 8-OxoG. Here, we report that in growing <i>B. subtilis</i> cells, the genetic inactiva...

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Bibliographic Details
Main Authors: Lissett E. Martínez, Gerardo Gómez, Norma Ramírez, Bernardo Franco, Eduardo A. Robleto, Mario Pedraza-Reyes
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Antioxidants
Subjects:
<i>Bacillus subtilis</i>
8-oxoG
GO system
mutagenesis
oxidative stress
Online Access:https://www.mdpi.com/2076-3921/13/3/332

Internet

https://www.mdpi.com/2076-3921/13/3/332

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