Comparative Structure–Activity Analysis of the Antimicrobial Activity, Cytotoxicity, and Mechanism of Action of the Fungal Cyclohexadepsipeptides Enniatins and Beauvericin

Comparative Structure–Activity Analysis of the Antimicrobial Activity, Cytotoxicity, and Mechanism of Action of the Fungal Cyclohexadepsipeptides Enniatins and Beauvericin

Filamentous fungi, although producing noxious molecules such as mycotoxins, have been used to produce numerous drugs active against human diseases such as paclitaxel, statins, and penicillin, saving millions of human lives. Cyclodepsipeptides are fungal molecules with potentially adverse and positiv...

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Bibliographic Details
Main Authors: Hamza Olleik, Cendrine Nicoletti, Mickael Lafond, Elise Courvoisier-Dezord, Peiwen Xue, Akram Hijazi, Elias Baydoun, Josette Perrier, Marc Maresca
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Toxins
Subjects:
cyclic fungal peptides
cyclohexadepsipeptide
enniatin
beauvericin
mycotoxin
antibiotic
antimicrobial peptide
AMP
<i>Clostridium perfringens</i>
Online Access:https://www.mdpi.com/2072-6651/11/9/514

Internet

https://www.mdpi.com/2072-6651/11/9/514

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