Exposing and Overcoming Limitations of Clinical Laboratory Tests in COVID-19 by Adding Immunological Parameters; A Retrospective Cohort Analysis and Pilot Study

Exposing and Overcoming Limitations of Clinical Laboratory Tests in COVID-19 by Adding Immunological Parameters; A Retrospective Cohort Analysis and Pilot Study

BackgroundTwo years since the onset of the COVID-19 pandemic no predictive algorithm has been generally adopted for clinical management and in most algorithms the contribution of laboratory variables is limited.ObjectivesTo measure the predictive performance of currently used clinical laboratory tes...

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Main Authors: Adrián Sánchez-Montalvá, Daniel Álvarez-Sierra, Mónica Martínez-Gallo, Janire Perurena-Prieto, Iria Arrese-Muñoz, Juan Carlos Ruiz-Rodríguez, Juan Espinosa-Pereiro, Pau Bosch-Nicolau, Xavier Martínez-Gómez, Andrés Antón, Ferran Martínez-Valle, Mar Riveiro-Barciela, Albert Blanco-Grau, Francisco Rodríguez-Frias, Pol Castellano-Escuder, Elisabet Poyatos-Canton, Jordi Bas-Minguet, Eva Martínez-Cáceres, Alex Sánchez-Pla, Coral Zurera-Egea, Aina Teniente-Serra, Manuel Hernández-González, Ricardo Pujol-Borrell, the “Hospital Vall d’Hebron Group for the study of COVID-19 immune profile”, Artur Llobell Uriel, Romina Dieli, Roger Colobran, Gemma Codina, Tomas Pumarola, Roser Ferrer, Vicente Cortina, Magda Campins, Isabel Ruiz, Nuria Fernaíndez, Esteban Ribera, Joan Roig, Ricardo Ferrer, Adolfo Ruiz-Sanmartín, Albert Selva, Moises Labrador, María José Soler Romeo, Jaume Ferrer, Eva Polverino, Antonio Alvarez, María Queralt Gorgas, Marta Miarons, Pere Soler-Palacin, Andrea Martin, Anna Suy, Maria Jose Buzón, Meritxell Genescà, Santiago Perez-Hoyos, Miriam Mota-Foix
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2 infection
predictive risk-profile
clinical laboratory tests
cytokines
chemokines
acute phase reactants
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.902837/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.902837/full

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