Losartan Reduces Remodeling and Apoptosis in an Adriamycin-Induced Cardiomyopathy Rat Model

Background: The use of Adriamycin (ADR), also known as doxorubicin, as a chemotherapy agent is limited by its detrimental adverse effects, especially cardiotoxicity. Recent studies have emphasized the crucial role of angiotensin II (Ang-II) in the development of ADR-induced cardiomyopathy. This s...

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Bibliographic Details
Main Authors: Hyeon A Kim, Kwan Chang Kim, Hyeryon Lee, Young Mi Hong
Format: Article
Language:English
Published: Korean Society for Thoracic & Cardiovascular Surgery 2023-09-01
Series:Journal of Chest Surgery
Subjects: