A seed expansion-based method to identify essential proteins by integrating protein–protein interaction sub-networks and multiple biological characteristics

A seed expansion-based method to identify essential proteins by integrating protein–protein interaction sub-networks and multiple biological characteristics

Abstract Background The identification of essential proteins is of great significance in biology and pathology. However, protein–protein interaction (PPI) data obtained through high-throughput technology include a high number of false positives. To overcome this limitation, numerous computational al...

Full description

Bibliographic Details
Main Authors: He Zhao, Guixia Liu, Xintian Cao
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Bioinformatics
Subjects:
Essential proteins
PPI sub-networks
Seed expand
Biological data
Online Access:https://doi.org/10.1186/s12859-023-05583-8

Internet

https://doi.org/10.1186/s12859-023-05583-8

Similar Items