Repeated Rounds of Gonadotropin Stimulation Induce Imbalance in the Antioxidant Machinery and Activation of Pro-Survival Proteins in Mouse Oviducts

Repeated Rounds of Gonadotropin Stimulation Induce Imbalance in the Antioxidant Machinery and Activation of Pro-Survival Proteins in Mouse Oviducts

Controlled ovarian stimulation (COS) through gonadotropin administration has become a common procedure in assisted reproductive technologies. COS’s drawback is the formation of an unbalanced hormonal and molecular environment that could alter several cellular mechanisms. On this basis, we detected t...

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Bibliographic Details
Main Authors: Valentina Di Nisio, Sevastiani Antonouli, Sabrina Colafarina, Osvaldo Zarivi, Gianna Rossi, Sandra Cecconi, Anna Maria Giuseppina Poma
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
oviducts
repeated ovarian stimulation
mtDNA fragmentation
antioxidant enzymes
pro-survival signaling
Online Access:https://www.mdpi.com/1422-0067/24/11/9294

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https://www.mdpi.com/1422-0067/24/11/9294

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